Detection and quantification of lung cancer biomarkers using a micro-analytical device

Detection and quantification of lung cancer biomarkers using a micro-analytical device

Jean-Baptiste Sanchez¹, Franck Berger¹, Igor Bezverkhyy²; Guy Weber², Jean-Pierre Bellat², Vanessa Fierro³, Alain Celzard³ 

1. lnstitut FEMTO-ST, UMR 6174, Universite de Bourgogne - Franche-Comte, CNRS, 15B, Avenue des montboucons, 25030 Besanc;on Cedex

2. Laboratoire lnterdisciplinaire Carnot de Bourgogne, UMR CNRS 6303, Universite de Bourgogne - Franc he Comte, 9 Avenue Alain Savary, BP 47870, 21078 Dijon

3. lnstitut Jean Lamour, UMR CNRS-Universite de Lorraine n°7198, ENSTIB 27 rue Philippe Seguin, BP 21042, 88051 Epinal Cedex 9

Full Poster: 

http://ow.ly/cf2630pU3ha

Abstract:

We present a prototype system for monitoring a set of potential lung cancer biomarkers: propanol-1, toluene, o-xylene and cyclohexane. This micro-analytical system consists of silicon gas preconcentrator containing a nanoporous zeolite sorbent, silicon gas chromatographic (GC) micro-column and a miniaturized single SnO2 -based gas sensor as detector. We show that the system can be used for quantification of traces of the mentioned biomarkers in the presence of H2O (90% RH) and CO2.

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