Passive Breath Profiling for Ultrasensitive Detection of Endogenously Produced VOCs using Electrochemical Methods
Ivneet Kaur Banga, Dr. Shalini Prasad
Biomedical Microdevices and Nanotechnology Lab
The University of Texas at Dallas, Richardson, TX -75080
Abstract: There are thousands of volatile organic compounds (VOCs) present in the exhaled breath that can provide insights into various respiratory diseases, such as lung cancer, chronic kidney disease, asthma, chronic obstructive pulmonary disease (COPD), and coronavirus. The metabolomics study of the exhaled air or breathomics can be used to find a set of markers (breath prints) that can point to abnormalities in the body's function. The advancements in the development of analytic platforms have led to the increased use of VOCs as markers of exposure to disease. They enable rapid, non-invasive, and low-cost diagnostics that can be performed at the patient's bedside and expedite decision-making. As per a recent report, the current Point of Care (POC) market in the United States exceeds $20 billion. My doctoral research on passive breath profiling for ultrasensitive detection of endogenously produced VOCs using electrochemical methods is inspired by the growing interest in the field of non-invasive detection methods and in-depth research on the use of breath as a fingerprint for disease diagnosis.